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1

The psychotropic drug olanzapine (Zyprexa®) increases the area of acid glycerophospholipid monolayers

Signe Steinkopf, Anja Katrin Schelderup, Hanne Linn Gjerde, Jeanette Pfeiffer, Synnøve Thoresen, Anja Underhaug Gjerde, Holm Holmsen

Journal:

Biophysical Chemistry

Year:

2008

Language:

english

File:

PDF, 619 KB

english, 2008

2

Time-dependent inhibitory effects of cGMP-analogues on thrombin-induced platelet-derived microparticles formation, platelet aggregation, and P-selectin expression

Nygaard, Gyrid, Herfindal, Lars, Kopperud, Reidun, Aragay, Anna M., Holmsen, Holm, Døskeland, Stein Ove, Kleppe, Rune, Selheim, Frode

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 758 KB

english, 2014

3

Tuning micelles of a bioactive heptapeptide biosurfactant via extrinsically induced conformational transition of surfactin assembly

Mohamad Osman, Harald Høiland, Holm Holmsen, Yutaka Ishigami

Journal:

Journal of Peptide Science

Year:

1998

Language:

english

File:

PDF, 121 KB

english, 1998

4

Hydrogen peroxide, an inhibitor of platelet function: Effect on adenine nucleotide metabolism, and the release reaction

Dr. Marie J. Stuart, Holm Holmsen

Journal:

American Journal of Hematology

Year:

1977

Language:

english

File:

PDF, 674 KB

english, 1977

5

Platelet-activating factor is a weak platelet agonist: Evidence from normal human platelets and platelets with congenital secretion defects

A. Koneti Rao, Janet Willis, Barbara Hassell, Carol Dangelmaier, Holm Holmsen, J. Bryan Smith

Journal:

American Journal of Hematology

Year:

1984

Language:

english

File:

PDF, 793 KB

english, 1984

6

Activated platelet-derived growth factor autocrine pathway drives the transformed phenotype of a human glioblastoma cell line

Flemming S. Vassbotn, Arne Östman, Nina Langeland, Holm Holmsen, Bengt Westermark, Carl-Henrik Heldin, Monica Nistér

Journal:

Journal of Cellular Physiology

Year:

1994

Language:

english

File:

PDF, 1.03 MB

english, 1994

7

Microdetermination of adenosine diphosphate and adenosine triphosphate in plasma with the firefly luciferase system

Holm Holmsen, Inger Holmsen, Arvid Bernhardsen

Journal:

Analytical Biochemistry

Year:

1966

Language:

english

File:

PDF, 3.36 MB

english, 1966

8

Determination of ATP and ADP in blood platelets: A modification of the firefly luciferase assay for plasma

Holm Holmsen, Eva Storm, H. James Day

Journal:

Analytical Biochemistry

Year:

1972

Language:

english

File:

PDF, 719 KB

english, 1972

9

Determination of acid hydrolases in human platelets

Carol A. Dangelmaier, Holm Holmsen

Journal:

Analytical Biochemistry

Year:

1980

Language:

english

File:

PDF, 726 KB

english, 1980

10

Determination of levels of glycolytic intermediates and nucleotides in platelets by pulse-labeling with [32P]orthophosphate

Holm Holmsen, Carol A. Dangelmaier, Jan-Willem N. Akkerman

Journal:

Analytical Biochemistry

Year:

1983

Language:

english

File:

PDF, 996 KB

english, 1983

11

Use of actin-bound adenosine 5′-diphosphate as a method to determine the specific 32P-radioactivity of the γ-phosphoryl group of adenosine 5′-triphosphate in a highly compartmentalized cell, the platelet

Adrie J.M. Verhoeven, Carol A. Cook, Holm Holmsen

Journal:

Analytical Biochemistry

Year:

1988

Language:

english

File:

PDF, 609 KB

english, 1988

12

Stimulation of human platelets with low concentrations of thrombin: Evidence for equimolar accumulation of inositol trisphosphates and phosphatidic acid

Ole-Bjørn Tysnes, Vidar M. Steen, Grethe M. Aarbakke, Holm Holmsen

Journal:

International Journal of Biochemistry

Year:

1991

Language:

english

File:

PDF, 636 KB

english, 1991

13

Existence of lipid microdomains in bilayer of dipalmitoyl phosphatidylcholine (DPPC) and 1-stearoyl-2-docosahexenoyl phosphatidylserine (SDPS) and their perturbation by chlorpromazine : A 13C and 31P solid-state NMR study

Chen Song, Holm Holmsen, Willy Nerdal

Journal:

Biophysical Chemistry

Year:

2006

Language:

english

File:

PDF, 260 KB

english, 2006

14

pH-dependent interaction of psychotropic drug with glycerophospholipid monolayers studied by the Langmuir technique

Signe Steinkopf, Aida Simeunović, Helene J. Bustad, Thi Ha Ngo, Hege Sveaass, Anja U. Gjerde, Holm Holmsen

Journal:

Biophysical Chemistry

Year:

2010

Language:

english

File:

PDF, 702 KB

english, 2010

15

Chlorpromazine associates with phosphatidylserines to cause an increase in the lipid's own interfacial molecular area — role of the fatty acyl composition

Armelle Varnier Agasøster, Holm Holmsen

Journal:

Biophysical Chemistry

Year:

2001

Language:

english

File:

PDF, 170 KB

english, 2001

16

Interaction of triclosan with eukaryotic membrane lipids

Henning Lygre, Grete Moe, Rita Skålevik, Holm Holmsen

Journal:

European Journal of Oral Sciences

Year:

2003

Language:

english

File:

PDF, 186 KB

english, 2003

17

Dynamic transition of α-helix to β-sheet structure in linear surfactin correlating to critical micelle concentration

Mohamad Osman, Yutaka Ishigami, Keiichiro Ishikawa, Yasuko Ishizuka, Holm Holmsen

Journal:

Biotechnology Letters

Year:

1994

Language:

english

File:

PDF, 421 KB

english, 1994

18

Interaction of a dental filling material eluate and membrane lipids

Henning Lygre, Marta Vorland, Holm Holmsen

Journal:

Clinical Oral Investigations

Year:

2001

Language:

english

File:

PDF, 56 KB

english, 2001

19

In thrombin stimulated human platelets Citalopram, Promethazine, Risperidone, and Ziprasidone, but not Diazepam, may exert their pharmacological effects also through intercalation in membrane phospholipids in a receptor-independent manner

Ramadhan Oruch, Erlend Hodneland, Ian F. Pryme, Holm Holmsen

Journal:

Journal of Chemical Biology

Year:

2009

Language:

english

File:

PDF, 498 KB

english, 2009

20

An intercalation mechanism as a mode of action exerted by psychotropic drugs: results of altered phospholipid substrate availabilities in membranes?

Ramadhan Oruch, Anders Lund, Ian F. Pryme, Holm Holmsen

Journal:

Journal of Chemical Biology

Year:

2010

Language:

english

File:

PDF, 1.34 MB

english, 2010

21

Polyethylene glycols interact with membrane glycerophospholipids: is this part of their mechanism for hypothermic graft protection?

Delphine Dutheil, Anja Underhaug Gjerde, Isabelle Petit-Paris, Gérard Mauco, Holm Holmsen

Journal:

Journal of Chemical Biology

Year:

2009

Language:

english

File:

PDF, 499 KB

english, 2009

22

Importance of polyunsaturated acyl chains in chlorpromazine interaction with phosphatidylserines: A 13C and 31P solid-state NMR study

Song Chen, Anja Underhaug Gjerde, Holm Holmsen, Willy Nerdal

Journal:

Biophysical Chemistry

Year:

2005

Language:

english

File:

PDF, 306 KB

english, 2005

23

pH-dependent drug interaction with glycerophospholipid monolayers studied by the Langmuir technique

Helene Bustad Johannessen, Ha Thi Ngo, Aida Simeunovic, Hege Sveaass, Signe Steinkopf, Anja Underhaug Gjerde, Holm Holmsen

Journal:

Chemistry and Physics of Lipids

Year:

2007

Language:

english

File:

PDF, 62 KB

english, 2007

24

Inhibition of thrombin-stimulated phospholipase A2 activity in human platelets by psychotropics

Ramadhan Oruch, Holm Holmsen

Journal:

Chemistry and Physics of Lipids

Year:

2007

Language:

english

File:

PDF, 58 KB

english, 2007

25

A dominant role of thromboxane formation in secondary aggregation of platelets

Meyers, Kenneth M., Seachord, Carrie L., Holmsen, Holm, Smith, J. Bryan, Prieur, David J.

Journal:

Year:

1979

File:

PDF, 319 KB

1979

26

Choline derived from the phosphatidylcholine specific phospholipase D is not directly available for the CDP choline pathway in phorbol ester- treated C3H10T1/2 C18 fibroblasts

Vidar A.T. Thorsen, Ove Bruland, Johan R. Lillehaug, Holm Holmsen

Journal:

Molecular and Cellular Biochemistry

Year:

1998

Language:

english

File:

PDF, 120 KB

english, 1998

27

The stimulatory effects of cationic amphiphilic drugs on human platelets treated with thrombin

Pasupathy Tharmapathy, Miriam H Fukami, Holm Holmsen

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 492 KB

english, 2000

28

Chorpromazine-induced increase in dipalmitoylphosphatidylserine surface area in monolayers at room temperature

Armelle Varnier Agasøsler, Laila M. Tungodden, Daniel Čejka, Einar Bakstad, Leiv K. Sydnes, Holm Holmsen

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 298 KB

english, 2001

29

Chlorpromazine and human platelet glycerolipid metabolism: precursor specificity and significance of drug–platelet interaction time

Knut Olav Daasvatn, Holm Holmsen

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 413 KB

english, 1999

30

Role of autocrine stimulation on the effects of cyclic AMP on protein and lipid phosphorylation in collagen-activated and thrombin-activated platelets

Anita Ryningen, Baard Olav Jensen, Holm Holmsen

Journal:

Year:

1999

Language:

english

File:

PDF, 632 KB

english, 1999

31

Platelet Function – Assessment, Diagnosis and Treatment

Journal:

European Journal of Haematology

Year:

2006

Language:

english

File:

PDF, 65 KB

english, 2006

32

Hereditary Defect in the Platelet Release Reaction Caused by a Deficiency in the Storage Pool of Platelet Adenine Nucleotides

Holm Holmsen, Harvey J. Weiss

Journal:

British Journal of Haematology

Year:

1970

Language:

english

File:

PDF, 489 KB

english, 1970

33

Storage of Human Platelets: Effects on Metabolically Active ATP and on the Release Reaction

Barbara Kotelba-Witkowska, Holm Holmsen, Erik H. Murer

Journal:

British Journal of Haematology

Year:

1972

Language:

english

File:

PDF, 540 KB

english, 1972

34

The Role of Thrombin in ADP-Induced Platelet Aggregation and Release: a Critical Evaluation

Donald E. Macfarlane, Peter N. Walsh, David C. B. Mills, Holm Holmsen, H. James Day

Journal:

British Journal of Haematology

Year:

1975

Language:

english

File:

PDF, 415 KB

english, 1975

35

Abnormal Platelet Function in Chediak-Higashi Syndrome

Grace Jordison Boxer, Holm Holmsen, Linda Robkin, Nils U. Bang, Laurence A. Boxer, Robert L. Baehner

Journal:

British Journal of Haematology

Year:

1977

Language:

english

File:

PDF, 797 KB

english, 1977

36

The storage pool deficiency in platelets from humans with the Chédiak-Higashi syndrome: study of six patients

Rafael Apitz-Castro, Maria Rosa Cruz, Eliades Ledezma, Fernando Merino, Pedro Ramirez-Duque, Carol Dangelmeier, Holm Holmsen

Journal:

British Journal of Haematology

Year:

1985

Language:

english

File:

PDF, 823 KB

english, 1985

37

Subcellular Particles of Human Platelets : A Biochemical and Electronmicroscopic Study with Particular Reference to the Influence of Fractionation Techniques

H. James Day, Holm Holmsen, , Torstein Hovig

Journal:

European Journal of Haematology

Year:

1969

Language:

english

File:

PDF, 7.65 MB

english, 1969

38

The Blood Platelet Release Reaction

Holm Holmsen, , H. James Day, Helge Stormorken

Journal:

European Journal of Haematology

Year:

1969

Language:

english

File:

PDF, 1.55 MB

english, 1969

39

ADP-Induced Refractory State of Platelets in vitro : I. Methodological Studies on Aggregation in Platelet Rich Plasma

Stein Holme, Holm Holmsen

Journal:

European Journal of Haematology

Year:

1975

Language:

english

File:

PDF, 486 KB

english, 1975

40

ADP-Induced Refractory State of Platelets in Vitro II. Functional and Ultra Studies on Gel Filtered Platelets

Stein Holme, Jan J. Sixma, Jaap Wester, Holm Holmsen

Journal:

European Journal of Haematology

Year:

1977

Language:

english

File:

PDF, 1.42 MB

english, 1977

41

Current aspects on human platelet activation and responses

Vidar M. Steen, Holm Holmsen

Journal:

European Journal of Haematology

Year:

1987

Language:

english

File:

PDF, 1.41 MB

english, 1987

42

Porcine platelets in vitro and in vivo studies: Relevance to human thrombosis research

Eirik Søfteland, Tore Framstad, Terje Thorsen, Holm Holmsen

Journal:

European Journal of Haematology

Year:

1992

Language:

english

File:

PDF, 1.28 MB

english, 1992

43

Energy Metabolism and Platelet Responses

Journal:

Year:

1981

Language:

english

File:

PDF, 472 KB

english, 1981

44

Nucleotide exchange between cytosolic ATP and F-actin-bound ADP may be a major energy-utilizing process in unstimulated platelets

James L. DANIEL, Ilean R. MOLISH, Linda ROBKIN, Holm HOLMSEN

Journal:

Year:

1986

Language:

english

File:

PDF, 807 KB

english, 1986

45

Turnover of the phosphomonoester groups of polyphospoinositol lipids in unstimulated human platelets

Adrie J. M. VERHOEVEN, Ole-Bjørn TYSNES, Grethe M. AARBAKKE, Carol A. COOK, Holm HOLMSEN

Journal:

Year:

1987

Language:

english

File:

PDF, 832 KB

english, 1987

46

Rates of production and consumption of phosphatidic acid upon thrombin stimulation of human platelets

Ole-Bjørn TYSNES, Adrie J. M. VERHOEVEN, Holm HOLMSEN

Journal:

Year:

1988

Language:

english

File:

PDF, 514 KB

english, 1988

47

Neomycin inhibits platelet functions and inositol phospholipid metabolism upon stimulation with thrombin, but not with ionomycin or 12-O-tetradecanoyl-phorbol 13-acetate

Ole-BjØrn TYSNES, Vidar M. STEEN, Holm HOLMSEN

Journal:

Year:

1988

Language:

english

File:

PDF, 490 KB

english, 1988

48

Diacylglycerol Elevations in Control Platelets are Unaccompanied by Pleckstrin Phosphorylation : Implications for the Role of Diacylglycerol in Platelet Activation

Miriam H. Fukami, Holm Holmsen

Journal:

Year:

1995

Language:

english

File:

PDF, 930 KB

english, 1995

49

Thrombin per se Does Not Induce Tyrosine Protein Phosphorylation in Human Platelets as Judged by Western Blotting, While Collagen Does: The Significance of Synergistic, Autocrine Stimulation

Anita Ryningen, Holm Holmsen

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 312 KB

english, 1998

50

Formation of PI 3-Kinase Products in Platelets by Thrombin, but Not Collagen, Is Dependent on Synergistic Autocrine Stimulation, Particularly through Secreted ADP

Frode Selheim, Randi Idsøe, Miriam H. Fukami, Holm Holmsen, Flemming S. Vassbotn

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 223 KB

english, 1999